Non-ARV/Non-Hormonal Multi-Purpose Vaginal Ring
The non-antiretroviral, non-hormonal intravaginal ring developed by the Oak Crest Institute of Science is a multipurpose prevention technology with a 1-to 3-month duration combining two novel, luminally acting active pharmaceutical ingredients: (1) an antiviral with unique mechanisms of action against HSV; and (2) a contraceptive and would be a game-changer product for women who desire non-hormonal contraceptives with prevention of HSV and other sexually transmitted infections in a single product. Gathering end-user feedback early in the design phase will be prioritized. First-in-human trials will evaluate the safety and pharmacokinetics of the multipurpose prevention technology.
For more information, contact: Marc Baum at m.baum@oak-crest.org
Development Stage:
Preclinical – Advanced (Pre2)
Hormonal/Non-Hormonal:
Non-Hormonal
Delivery Route & Method:
Intravaginal - Intravaginal Ring (IVR)
Developer:
- Oak Crest Institute of Science
Funding:
- National Institutes of Health (NIH)
Funding Mechanism:
NIH
Past Funding:
USAID
Active Ingredient(s):
- Soluble adenylyl cyclase (sAC)
- Antiviral peptide lead candidate
Product Indication(s):
- HSV-1
- HSV-2
- Unintended Pregnancy