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Non-ARV/Non-Hormonal Multi-Purpose Vaginal Ring

The non-antiretroviral, non-hormonal intravaginal ring developed by the Oak Crest Institute of Science is a multipurpose prevention technology with a 1-to 3-month duration combining two novel, luminally acting active pharmaceutical ingredients: (1) an antiviral with unique mechanisms of action against HIV, HSV, and HPV; and (2) a contraceptive and would be a game-changer product for women who desire non-hormonal contraceptives with prevention of HIV and other sexually transmitted infections in a single product. Gathering end-user feedback early in the design phase will be prioritized. First-in-human trials will evaluate the safety and pharmacokinetics of the multipurpose prevention technology.

For more information, contact: Marc Baum at

Development Stage:

Preclinical – Advanced (Pre2)



Delivery Route & Method:

Intravaginal - Intravaginal Ring (IVR)


  • Oak Crest Institute of Science


  • U.S. Agency for International Development (USAID)

Active Ingredient(s):

  • Unspecified

Product Indication(s):

  • HIV
  • HPV
  • HSV-1
  • HSV-2
  • Pregnancy

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