Multipurpose Prevention Technologies (MPTs) are an innovative class of products that deliver varied combinations of HIV prevention, other STI prevention, and contraception and will improve the lives of women and families worldwide.

This database includes MPT products that are currently funded and in active development. The database outlines detailed product information and can be searched to display products by desired criteria as selected from the drop-down boxes or by entering a keyword in the search box. Click on the product name to access detailed information on each product. Please note there are other MPT candidates not listed that may move forward pending funding.

Click here to learn more about the inclusion criteria and information update methodology.

Click on the tables for MPT products in the development pipeline, listed by:

Click on the image to download graphics of MPT products in the development pipeline:

Search MPT Product Development Database

Hormonal / Non-Hormonal

Delivery Route

Delivery Method

Development Stage

Indication

Product Developer

Product Sponsor / Funding

Active Ingredient(s)

Click on the product name for more details.

Name                                            
Hormonal Type
Delivery Route
Delivery Method
Active Ingredients
Product Developer
Stage
Indications
Hormonal
Topical
Intravaginal Ring (IVR)
  • Etonogestrel
  • Ethinyl Estradiol
  • QGRFT
  • Oak Crest Institute of Science
  • Population Council
Pre1
  • HIV
  • Pregnancy
Non-Hormonal
Topical
Fast Dissolving Insert/Capsule-Vaginal
  • Citric Acid
  • L-lactic Acid
  • Potassium Bitartrate
  • Evofem Biosciences, Inc.
  • Population Council
Pre1
  • Bacterial Vaginosis (BV)
  • Chlamydia
  • Gonorrhea
  • Pregnancy
Non-Hormonal
Topical
Fast Dissolving Insert/Capsule-Vaginal
  • Citric Acid
  • L-lactic Acid
  • Potassium Bitartrate
  • QGRFT
  • Evofem Biosciences, Inc.
  • Population Council
Pre1
  • Bacterial Vaginosis (BV)
  • Chlamydia
  • Gonorrhea
  • HIV
  • Pregnancy
Hormonal
Systemic
Injectable (Subcutaneous)
  • Integrase Inhibitors
  • Levonorgestrel
  • CONRAD
Pre2
  • HIV
  • Pregnancy
Non-Hormonal
Topical
Intravaginal Ring (IVR)
  • Copper
  • University of California, Davis
Pre1
  • HSV-2
  • Pregnancy
  • Zika virus (ZIKV)
Hormonal
Topical
Intravaginal Ring (IVR)
  • Dapivirine
  • Levonorgestrel
  • International Partnership for Microbicides (IPM)
C1
  • HIV
  • Pregnancy
Hormonal
Topical
Intravaginal Ring (IVR)
  • Dapivirine
  • Levonorgestrel
  • Pritelivir
  • University of North Carolina, Chapel Hill
Pre1
  • HIV
  • HSV-2
  • Pregnancy
Hormonal
Topical
Intravaginal Ring (IVR)
  • Acyclovir
  • Dolutegravir
  • Etonogestrel
  • Ethinyl Estradiol
  • Rilpivirine
  • Auritec Pharmaceuticals
Pre2
  • HIV
  • HSV-2
  • Pregnancy
Hormonal
Systemic
Pill/Tablet- Oral
  • Combined Oral Contraceptive (COC)
  • Emtricitabine (FTC)
  • Ethinyl Estradiol (EE)
  • Levonorgestrel
  • Tenofovir Disoproxil Fumarate (TDF)
  • Population Council
Post-marketing
  • HIV
  • Pregnancy
Hormonal
Topical
Film - Vaginal
  • 4'-Ethynyl-2-fluoro-2'-deoxyadenosine prodrug (EFdA-P)
  • Progestin
  • Magee-Women's Research Inst. & Foundation
Pre1
  • HIV
  • Pregnancy
Non-Hormonal
Topical
Gel-Vaginal
  • Citric Acid
  • L-lactic Acid
  • Potassium Bitartrate
  • Evofem Biosciences, Inc.
C3
  • Chlamydia
  • Gonorrhea
  • Pregnancy
Non-Contraceptive
Topical
Gel-Rectal
  • Griffithsin (GRFT)
  • University of Louisville
Pre1
  • Hepatitis
  • HIV
  • HSV-2
Non-Hormonal
Topical
Intravaginal Ring (IVR)
  • HCA
  • Monoclonal Antibodies
  • VRC01 + N6
  • MUCOMMUNE LLC
Pre2
  • HIV
  • Pregnancy
Hormonal
Topical
Intravaginal Ring (IVR)
  • Etonogestrel
  • Ethinyl Estradiol
  • Islatravir (EFdA)
  • University of North Carolina, Chapel Hill
Pre1
  • HIV
  • Pregnancy
Non-Contraceptive
Topical
Intravaginal Ring (IVR)
  • Monoclonal Antibodies
  • Tenofovir Disoproxil Fumarate (TDF)
  • MassBiologics
  • Oak Crest Institute of Science
  • Planet Biotechnology, Inc.
  • University of Massachusetts
Pre2
  • Gonorrhea
  • HIV
Non-Contraceptive
Topical
Gel-Vaginal;Rectal
  • Carrageenan
  • MIV-150
  • Zinc Acetate
  • Population Council
C2
  • HIV
  • HPV
  • HSV-2
Hormonal
Systemic
Microarray Patch
  • Cabotegravir
  • Norelgestromin
  • PATH
  • Queens University Belfast
Pre1
  • HIV
  • Pregnancy
Non-Hormonal
Topical
Intravaginal Ring (IVR)
  • Monoclonal Antibodies
  • Tenofovir Disoproxil Fumarate (TDF)
  • Oak Crest Institute of Science
  • University of North Carolina, Chapel Hill
Pre1
  • HIV
  • Pregnancy
Non-Contraceptive
Topical
Enema - Rectal
  • QGRFT
  • University of Louisville
  • University of Pittsburgh
C1
  • Hepatitis
  • HIV
  • HPV
  • HSV-2
Hormonal
Systemic
Implant (Subcutaneous)
  • Unspecified
  • Research Triangle International (RTI)
Pre1
  • HIV
  • Pregnancy
Non-Contraceptive
Topical
Fast Dissolving Insert – Vaginal, Rectal
  • Elvitegravir
  • Tenofovir Alafenamide (TAF)
  • CONRAD
C1
  • HIV
  • HSV-2
Hormonal
Topical
Intravaginal Ring (IVR)
  • Levonorgestrel
  • Tenofovir (TFV)
  • CONRAD
C2
  • HIV
  • HSV-2
  • Pregnancy
Non-Contraceptive
Topical
Intravaginal Ring (IVR)
  • Tenofovir (TFV)
  • CONRAD
C2
  • HIV
  • HSV-2
Non-Contraceptive
Topical
Film - Vaginal
  • Efavirenz (EFV)
  • Tenofovir (TFV)
  • Inst. for Research & Innovation in Health (i3S), U. of Porto
Pre2
  • HIV
  • HSV-1
  • HSV-2
Hormonal
Systemic
Injectable In-situ Forming Implant (Subcutaneous)
  • Hormonal Contraceptive
  • Antiretroviral (ARV)
  • University of North Carolina, Chapel Hill
Pre1
  • HIV
  • Pregnancy
Non-Contraceptive
Topical
Gel-Vaginal
  • SPL7013 (Astodrimer Sodium)
  • Starpharma Pty Limited
Pre2
  • Bacterial Vaginosis (BV)
  • HIV
  • HPV
  • HSV-2
Non-Hormonal
Topical
Gel-Vaginal
  • Polyphenylene Carboxymethylene (PPCM)
  • Yaso Therapeutics
Pre2
  • Gonorrhea
  • HIV
  • HPV
  • HSV-2
  • Pregnancy

MPT Product Types in Development

Resources on single indication products

  • Calliope, the Contraceptive Pipeline Database, includes information about more than 170 contraceptive leads and products, including male and female targets and hormonal and non-hormonal methods. Visit the Calliope database at pipeline.ctiexchange.org.
  • The Contraceptive Technology Innovation (CTI) Exchange is a platform for increasing global access to resources on contraceptive research, development, registration, and introduction through collaboration and knowledge sharing. Visit the CTI Exchange at www.ctiexchange.org.
  • The HIV Prevention Research & Development Database (PxRD) is a comprehensive resource on biomedical HIV prevention clinical trials that are planned, ongoing or completed. Visit the PxRD database at www.avac.org/pxrd.

Feedback

Know of an MPT product not included in this database or have updated information for listed products? Let us know here!

MPT DATABASE FEEDBACK