Multipurpose Prevention Technologies (MPTs) are an innovative class of products that deliver varied combinations of HIV prevention, other STI prevention, and contraception and will improve the lives of women and families worldwide.
This database includes MPT products that are currently funded and in active development as of September 2023. The database outlines detailed product information and can be searched to display products by desired criteria as selected from the drop-down boxes or by entering a keyword in the search box. Click on the product name to access detailed information on each product. Please note there are other MPT candidates not listed that may move forward pending funding.
Click here to learn more about the inclusion criteria and information update methodology.
Click on the tables for MPT products in the development pipeline, listed by:
Click to download graphics of MPT products in the development pipeline as of September 2023:
If you refer to this database, please use the following suggested citation: The IMPT. (2023). MPT Product Development Database. MPTs101.org.
Search MPT Product Development Database
Hormonal / Non-Hormonal
Delivery Route
Delivery Method
Development Stage
Indication
Product Developer
Product Sponsor / Funding
Active Ingredient(s)
Click on the product name for more details.
- Etonogestrel
- Ethinyl Estradiol
- QGRFT
- Oak Crest Institute of Science
- Population Council
- Pre1
- HIV
- Pregnancy
- Cabotegravir
- Levonorgestrel
- CONRAD
- Pre1
- HIV
- Pregnancy
- Cabotegravir
- Levonorgestrel
- CONRAD
- Pre2
- HIV
- Pregnancy
- Copper
- University of California, Davis
- Pre1
- HSV-2
- Pregnancy
- Zika virus (ZIKV)
- Dapivirine
- Levonorgestrel
- Population Council
- C1
- HIV
- Pregnancy
- Dapivirine
- Levonorgestrel
- Pritelivir
- University of North Carolina, Chapel Hill
- Pre1
- HIV
- HSV-2
- Pregnancy
- Dapivirine
- Levonorgestrel
- Magee-Women's Research Inst. & Foundation
- University of Pittsburgh
- Pre1
- HIV
- Pregnancy
- Emtricitabine (FTC)
- Ethinyl Estradiol (EE)
- Levonorgestrel
- Tenofovir Disoproxil Fumarate (TDF)
- Viatris
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Clinical – Bioequivalence Study
- HIV
- Pregnancy
- Emtricitabine (FTC)
- Ethinyl Estradiol (EE)
- Levonorgestrel
- Tenofovir Alafenamide (TAF)
- Population Council
- Medicines360
- Pre1
- HIV
- Pregnancy
- 4'-Ethynyl-2-fluoro-2'-deoxyadenosine (EFdA)
- 4'-Ethynyl-2-fluoro-2'-deoxyadenosine prodrug (EFdA-P)
- Progestin
- Magee-Women's Research Inst. & Foundation
- University of Pittsburgh
- Pre1
- HIV
- Pregnancy
- Unspecified
- Population Council
- Pre-formulation
- HIV
- HPV
- HSV-1
- HSV-2
- HCA
- Monoclonal Antibodies
- VRC01 + N6
- MUCOMMUNE LLC
- Pre2
- HIV
- Pregnancy
- Etonogestrel
- Ethinyl Estradiol
- Islatravir (EFdA)
- University of North Carolina, Chapel Hill
- Pre1
- HIV
- Pregnancy
- Etonogestrel
- Islatravir (EFdA)
- University of Washington
- Methodist Hospital Research Institute (HMRI)
- Pre1
- HIV
- Pregnancy
- Monoclonal Antibodies
- Tenofovir Disoproxil Fumarate (TDF)
- MassBiologics
- Oak Crest Institute of Science
- Planet Biotechnology, Inc.
- University of Massachusetts
- Pre2
- Gonorrhea
- HIV
- Unspecified
- Oak Crest Institute of Science
- Pre-formulation
- HIV
- HPV
- HSV-1
- HSV-2
- Pregnancy
- QGRFT
- Organic acids
- Population Council
- Pre1
- Bacterial Vaginosis (BV)
- Chlamydia
- Gonorrhea
- HIV
- HSV-2
- Pregnancy
- Copper
- Zinc
- Lactide
- Population Council
- Queen's University Belfast
- Weill Cornell Medical College
- Pre-formulation
- pre-Phase 1 Clinical Trials among end-users
- Non-clinical
- Bacterial Vaginosis (BV)
- Chlamydia
- Gonorrhea
- HIV
- HSV-2
- Pregnancy
- Monoclonal Antibodies
- Tenofovir Disoproxil Fumarate (TDF)
- Oak Crest Institute of Science
- University of North Carolina, Chapel Hill
- Pre1
- HIV
- Pregnancy
- Elvitegravir
- Tenofovir Alafenamide (TAF)
- CONRAD
- C1
- HIV
- HSV-2
- Efavirenz (EFV)
- Tenofovir (TFV)
- Inst. for Research & Innovation in Health (i3S), U. of Porto
- Pre2
- HIV
- HSV-1
- HSV-2
- Hormonal Contraceptive
- Antiretroviral (ARV)
- University of North Carolina, Chapel Hill
- Pre1
- HIV
- Pregnancy
- SPL7013 (Astodrimer Sodium)
- Starpharma Pty Limited
- C3
- INT
- Bacterial Vaginosis (BV)
- HIV
- HPV
- HSV-2
- Polyphenylene Carboxymethylene (PPCM)
- Yaso Therapeutics
- Pre2
- Gonorrhea
- HIV
- HPV
- HSV-2
- Pregnancy
MPT Product Types in Development
Resources on single indication products
- Calliope, the Contraceptive Pipeline Database, includes information about more than 170 contraceptive leads and products, including male and female targets and hormonal and non-hormonal methods. Visit the Calliope database at pipeline.ctiexchange.org.
- The Contraceptive Technology Innovation (CTI) Exchange is a platform for increasing global access to resources on contraceptive research, development, registration, and introduction through collaboration and knowledge sharing. Visit the CTI Exchange at www.ctiexchange.org.
- The HIV Prevention Research & Development Database (PxRD) is a comprehensive resource on biomedical HIV prevention clinical trials that are planned, ongoing or completed. Visit the PxRD database at www.avac.org/pxrd.
Feedback
Know of an MPT product not included in this database or have updated information for listed products? Let us know here!