Multipurpose Prevention Technologies (MPTs) are an innovative class of products that deliver varied combinations of HIV prevention, other STI prevention, and contraception and will improve the lives of women and families worldwide.
This database includes MPT products that are currently funded and in active development. The database outlines detailed product information and can be searched to display products by desired criteria as selected from the drop-down boxes or by entering a keyword in the search box. Click on the product name to access detailed information on each product. Please note there are other MPT candidates not listed that may move forward pending funding.
Click here to learn more about the inclusion criteria and information update methodology.
Click on the tables for MPT products in the development pipeline, listed by:
Click to download graphics of MPT products in the development pipeline as of December 2022:
Search MPT Product Development Database
Hormonal / Non-Hormonal
Delivery Route
Delivery Method
Development Stage
Indication
Product Developer
Product Sponsor / Funding
Active Ingredient(s)
Click on the product name for more details.
Name
Hormonal Type
Delivery Route
Delivery Method
Active Ingredients
Product Developer
Stage
Indications
Hormonal
Intravaginal
Intravaginal Ring (IVR)
- Etonogestrel
- Ethinyl Estradiol
- QGRFT
- Oak Crest Institute of Science
- Population Council
- Pre1
- HIV
- Pregnancy
Hormonal
Topical
Implant (Subcutaneous)
- Cabotegravir
- Levonorgestrel
- CONRAD
- Pre-formulation
- HIV
- Pregnancy
Hormonal
Systemic
Injectable (Subcutaneous)
- Cabotegravir
- Levonorgestrel
- CONRAD
- Pre2
- HIV
- Pregnancy
Non-Hormonal
Intravaginal
Intravaginal Ring (IVR)
- Copper
- University of California, Davis
- Pre1
- HSV-2
- Pregnancy
- Zika virus (ZIKV)
Hormonal
Intravaginal
Intravaginal Ring (IVR)
- Dapivirine
- Levonorgestrel
- International Partnership for Microbicides (IPM)
- C1
- HIV
- Pregnancy
Hormonal
Intravaginal
Intravaginal Ring (IVR)
- Dapivirine
- Levonorgestrel
- Pritelivir
- University of North Carolina, Chapel Hill
- Pre1
- HIV
- HSV-2
- Pregnancy
Hormonal
Topical
Film - Vaginal
- Dapivirine
- Levonorgestrel
- Magee-Women's Research Inst. & Foundation
- University of Pittsburgh
- Pre1
- HIV
- Pregnancy
Hormonal
Intravaginal
Intravaginal Ring (IVR)
- Acyclovir
- Dolutegravir
- Etonogestrel
- Ethinyl Estradiol
- Rilpivirine
- Auritec Pharmaceuticals
- Pre2
- HIV
- HSV-2
- Pregnancy
Hormonal
Systemic
Pill/Tablet- Oral
- Emtricitabine (FTC)
- Ethinyl Estradiol (EE)
- Levonorgestrel
- Tenofovir Disoproxil Fumarate (TDF)
- Viatris
- Clinical – Bioequivalence Study
- HIV
- Pregnancy
Hormonal
Systemic
Pill/Tablet- Oral
- Emtricitabine (FTC)
- Ethinyl Estradiol (EE)
- Levonorgestrel
- Tenofovir Alafenamide (TAF)
- Population Council
- Medicines360
- Clinical – Bioequivalence Study
- HIV
- Pregnancy
Hormonal
Topical
Film - Vaginal
- 4'-Ethynyl-2-fluoro-2'-deoxyadenosine (EFdA)
- 4'-Ethynyl-2-fluoro-2'-deoxyadenosine prodrug (EFdA-P)
- Progestin
- Magee-Women's Research Inst. & Foundation
- University of Pittsburgh
- Pre1
- HIV
- Pregnancy
Non-Hormonal
Topical
Gel-Vaginal
- Citric Acid
- L-lactic Acid
- Potassium Bitartrate
- Evofem Biosciences, Inc.
- C3
- Pregnancy
- Chlamydia and gonorrhea under clinical investigation
Non-Hormonal
Intravaginal
Intravaginal Ring (IVR)
- HCA
- Monoclonal Antibodies
- VRC01 + N6
- MUCOMMUNE LLC
- Pre2
- HIV
- Pregnancy
Hormonal
Intravaginal
Intravaginal Ring (IVR)
- Etonogestrel
- Ethinyl Estradiol
- Islatravir (EFdA)
- University of North Carolina, Chapel Hill
- Pre1
- HIV
- Pregnancy
Non-Contraceptive
Intravaginal
Intravaginal Ring (IVR)
- Monoclonal Antibodies
- Tenofovir Disoproxil Fumarate (TDF)
- MassBiologics
- Oak Crest Institute of Science
- Planet Biotechnology, Inc.
- University of Massachusetts
- Pre2
- Gonorrhea
- HIV
Hormonal
Systemic
Microarray Patch
- Norelgestromin
- ARV candidates under review
- PATH
- Queen's University Belfast
- Pre1
- HIV
- Pregnancy
Non-Hormonal
Intravaginal
Intravaginal Ring (IVR)
- Unspecified
- Oak Crest Institute of Science
- Pre-formulation
- HIV
- HPV
- HSV-1
- HSV-2
- Pregnancy
Non-hormonal Contraceptive Multipurpose Prevention Technology (MPT) Containing Q-Griffithsin (QGRFT)
Non-Hormonal
Topical
Fast Dissolving Insert/Capsule-Vaginal
- QGRFT
- Organic acids
- Population Council
- Pre1
- Bacterial Vaginosis (BV)
- Chlamydia
- Gonorrhea
- HIV
- HSV-2
- Pregnancy
Non-Hormonal
Intravaginal
Intravaginal Ring (IVR)
- Copper
- Zinc
- Lactide
- Population Council
- Queen's University Belfast
- Weill Cornell Medical College
- Pre-formulation
- pre-Phase 1 Clinical Trials among end-users
- Non-clinical
- Bacterial Vaginosis (BV)
- Chlamydia
- Gonorrhea
- HIV
- HSV-2
- Pregnancy
Non-Hormonal
Intravaginal
Intravaginal Ring (IVR)
- Monoclonal Antibodies
- Tenofovir Disoproxil Fumarate (TDF)
- Oak Crest Institute of Science
- University of North Carolina, Chapel Hill
- Pre1
- HIV
- Pregnancy
Hormonal
Systemic
Implant (Subcutaneous)
- Unspecified
- Research Triangle International (RTI)
- Pre1
- HIV
- Pregnancy
Non-Contraceptive
Topical
Fast Dissolving Insert – Vaginal, Rectal
- Elvitegravir
- Tenofovir Alafenamide (TAF)
- CONRAD
- C1
- HIV
- HSV-2
Hormonal
Intravaginal
Intravaginal Ring (IVR)
- Levonorgestrel
- Tenofovir (TFV)
- CONRAD
- C2
- HIV
- HSV-2
- Pregnancy
Non-Contraceptive
Topical
Film - Vaginal
- Efavirenz (EFV)
- Tenofovir (TFV)
- Inst. for Research & Innovation in Health (i3S), U. of Porto
- Pre2
- HIV
- HSV-1
- HSV-2
Hormonal
Systemic
Injectable In-situ Forming Implant (Subcutaneous)
- Hormonal Contraceptive
- Antiretroviral (ARV)
- University of North Carolina, Chapel Hill
- Pre1
- HIV
- Pregnancy
Non-Contraceptive
Topical
Gel-Vaginal
- SPL7013 (Astodrimer Sodium)
- Starpharma Pty Limited
- C3
- INT
- Bacterial Vaginosis (BV)
- HIV
- HPV
- HSV-2
Non-Hormonal
Topical
Gel-Vaginal
- Polyphenylene Carboxymethylene (PPCM)
- Yaso Therapeutics
- Pre2
- Gonorrhea
- HIV
- HPV
- HSV-2
- Pregnancy
MPT Product Types in Development
Resources on single indication products
- Calliope, the Contraceptive Pipeline Database, includes information about more than 170 contraceptive leads and products, including male and female targets and hormonal and non-hormonal methods. Visit the Calliope database at pipeline.ctiexchange.org.
- The Contraceptive Technology Innovation (CTI) Exchange is a platform for increasing global access to resources on contraceptive research, development, registration, and introduction through collaboration and knowledge sharing. Visit the CTI Exchange at www.ctiexchange.org.
- The HIV Prevention Research & Development Database (PxRD) is a comprehensive resource on biomedical HIV prevention clinical trials that are planned, ongoing or completed. Visit the PxRD database at www.avac.org/pxrd.
Feedback
Know of an MPT product not included in this database or have updated information for listed products? Let us know here!