Non-Hormonal Electrospun Mesh
Electrospun fibers were fabricated in a stacked architecture by blend electrospinning using polycaprolactone (PCL) as the backing layer for delivering NFP and cellulose acetate phthalate (CAP) as the top layer for delivering TFV. An analysis of surface morphology, mechanical and chemical properties, mucoadhesion, drug release profiles, encapsulation efficiency, and safety assessments was performed.
For more information, contact: Margaret Ilomuanya at milomuanya@unilag.edu.ng
Development Stage:
Preclinical – Early (Pre1)
Hormonal/Non-Hormonal:
Non-Hormonal
Delivery Route & Method:
Vaginal - Nanofiber-Vaginal
Developer:
- University of Lagos
Funding Mechanism:
MEDAFRICA Foundation Inc.
Scotch Plains, NJ, USA
Active Ingredient(s):
- Tenofovir (TFV)
- Nifedipine (NFP)
Product Indication(s):
- HIV
- Unintended Pregnancy