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Dual Prevention Pill (DPP) Regimen

An investigational 28-day contraceptive pill regimen that also provides protection against HIV. 21 pills will contain Emtricitabine and Tenofovir Alafenamide and EE/LNG; 7 pills will contain Emtricitabine and Tenofovir Alafenamide only.

Development Stage:

Preclinical – Early (Pre1)

Hormonal/Non-Hormonal:

Hormonal

Delivery Route & Method:

Systemic - Pill/Tablet- Oral

Mechanism of Action:

Emtricitabine and tenofovir alafenamide inhibit the viral replication of HIV. Ethinyl estradiol and levonorgestrel prevent ovulation.

Developer:

  • Population Council
  • Medicines360

Funding:

  • Gilead Sciences, Inc.
  • Population Council
  • Medicines360

Funding Mechanism:

(In-kind) Gilead Sciences, Inc.

Past Funding:

CIFF

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