Dual Prevention Pill (DPP) Regimen
An investigational 28-day contraceptive pill regimen that also provides protection against HIV. 21 pills will contain Emtricitabine and Tenofovir Alafenamide and EE/LNG; 7 pills will contain Emtricitabine and Tenofovir Alafenamide only.
Development Stage:
Clinical – Bioequivalence Study
Hormonal/Non-Hormonal:
Hormonal
Delivery Route & Method:
Systemic - Pill/Tablet- Oral
Mechanism of Action:
Emtricitabine and tenofovir alafenamide inhibit the viral replication of HIV. Ethinyl estradiol and levonorgestrel prevent ovulation.
Developer:
- Population Council
- Medicines360
Funding:
- Gilead Sciences, Inc.
- Population Council
- Medicines360
Past Funding:
CIFF
Active Ingredient(s):
- Emtricitabine (FTC)
- Ethinyl Estradiol (EE)
- Levonorgestrel
- Tenofovir Alafenamide (TAF)
Product Indication(s):
- HIV
- Pregnancy