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Dapivirine/Levonorgestrel Extended-Release Monthly Film

The multipurpose prevention technology (MPT) vaginal film being developed by the Rohan Pharmaceutics laboratory at the University of Pittsburgh School of Pharmacy and Magee-Womens Research Institute is a product providing monthly protection against HIV acquisition and unintended pregnancy. Building upon their innovative bioerodible vaginal film platform, this MPT product is being developed as a convenient, low-cost option with desirable features that are informed through end-user acceptability research. The product will undergo formulation optimization, preclinical testing (including studies in animal models such as macaques), IND-filing, and clinical testing in women.

For more information, contact: Lisa Rohan at lrohan@mwri.magee.edu

Development Stage:

Preclinical – Early (Pre1)

Hormonal/Non-Hormonal:

Hormonal

Delivery Route & Method:

Topical - Film - Vaginal

Developer:

  • Magee-Women's Research Inst. & Foundation
  • University of Pittsburgh

Funding:

  • U.S. Agency for International Development (USAID)

Active Ingredient(s):

  • Dapivirine
  • Levonorgestrel

Product Indication(s):

  • HIV
  • Pregnancy

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