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Cabotegravir/Levonorgestrel Long-Acting MPT Injectable

Silica hydrogel-based long-acting injectable delivering CAB and levonorgestrel for 3-6 months duration. Currently in preclinical development.

Development Stage:

Preclinical – Advanced (Pre2)

Hormonal/Non-Hormonal:

Hormonal

Delivery Route & Method:

Systemic - Injectable (Subcutaneous)

Mechanism of Action:

Integrase strand-transfer inhibitor; progestin

Developer:

  • CONRAD

Funding:

  • Eastern Virginia Medical School
  • National Institutes of Health (NIH)

Funding Mechanism:

NIH R33 (Project Horizon)

Past Funding:

National Institutes of Health (NIH R-61)

Active Ingredient(s):

  • Cabotegravir
  • Levonorgestrel

Product Indication(s):

  • HIV
  • Pregnancy

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