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Dapivirine + Pritelivir + Levonorgestrel 3D Printed IVR

Our paramount innovation is use of digital light synthesis – a novel 3D printing process known as continuous liquid interface production (CLIP™) – for rapid, scalable, and cost-effective manufacturing of geometrically and mechanically tunable, rationally designed intravaginal rings as platforms for multi-drug delivery.

For more information, contact: S. Rahima Benhabbour, MSc., PhD at benhabs@email.unc.edu

Development Stage:

Preclinical – Early (Pre1)

Hormonal/Non-Hormonal:

Hormonal

Delivery Route & Method:

Intravaginal - Intravaginal Ring (IVR)

Developer:

  • University of North Carolina, Chapel Hill

Funding:

  • U.S. Agency for International Development (USAID)

Funding Mechanism:

MATRIX/USAID/PATH

Past Funding:

NIAID: R61; Eshelman Institute for Innovation (EII)

Active Ingredient(s):

  • Dapivirine
  • Levonorgestrel
  • Pritelivir

Product Indication(s):

  • HIV
  • HSV-2
  • Pregnancy

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