This database includes MPT products that are currently in active development. The database outlines detailed product information and can be searched to display products by desired criteria as selected from the drop-down boxes or by entering a keyword in the search box. Click on the product name to access detailed information on each product. Please note there are other MPT candidates not listed that may move forward pending funding. Click here to learn more about the inclusion criteria and information update methodology.
Click on the table for MPT products in the development pipeline by indication combination.
Amphora lowers vaginal pH (pH = 3.5-4.5) in the presence of semen. The low pH inactivates sperm and bacteria. Gel coats vaginal and cervical mucosa and prevents sperm penetration. QGRFT is a potent non-ARV inhibitor of HIV. QGRFT binds to HIV envelope glycoproteins and prevents entry of HIV into target cells.
Developer:
Evofem Biosciences, Inc.
Population Council
Funding:
Nat. Institute Allergy & Infect. Diseases (NIAID)
National Institutes of Health (NIH)
Funding Mechanism:
NIH: R01 (NIAID)
Active Ingredient:
Citric Acid
L-lactic Acid
Potassium Bitartrate
QGriffithsin (QGRFT)
Product Indications:
Bacterial Vaginosis (BV)
Chlamydia
Gonorrhea
HIV
Pregnancy
Description: Multipurpose Vaginal pH Regulator (MVP-R™) with non-ARV (anti-retroviral) microbicide for the prevention of pregnancy and HIV.
