MPT Product Development Database

Multipurpose Prevention Technologies (MPTs) are an innovative class of products that deliver varied combinations of HIV prevention, other STI prevention, and contraception and will improve the lives of women and families worldwide.

This database includes MPT products that are currently in active development. The database outlines detailed product information and can be searched to display products by desired criteria as selected from the drop-down boxes or by entering a keyword in the search box. Click on the product name to access detailed information on each product. Please note there are other MPT candidates not listed that may move forward pending funding. Click here to learn more about the inclusion criteria and information update methodology.

Click on the tables for MPT products in the development pipeline, listed by:
 
 
Know of an MPT product not included in this database or have updated information for listed products? Let us know here!
 
Hormonal/Non-HormonalDelivery RouteDelivery MethodDevelopment Stage
       
IndicationProduct DeveloperProduct Sponsor/FundingActive Ingredient
       
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24 product(s) found



Amphora/QGriffithsin (QGRFT) fast-dissolving vaginal insert (FDI)

MPT in Development

Development Stage:
Preclinical – Early (Pre1)
Hormonal/Non-Hormonal:
Non-Hormonal
Delivery Route & Method:
Topical - Fast Dissolving Insert/Capsule-Vaginal
Mechanism of Action:
Amphora lowers vaginal pH (pH = 3.5-4.5) in the presence of semen. The low pH inactivates sperm and bacteria. Gel coats vaginal and cervical mucosa and prevents sperm penetration. QGRFT is a potent non-ARV inhibitor of HIV. QGRFT binds to HIV envelope glycoproteins and prevents entry of HIV into target cells.
Developer:
  • Evofem Biosciences, Inc.
  • Population Council
  • Funding:
  • Nat. Institute Allergy & Infect. Diseases (NIAID)
  • National Institutes of Health (NIH)
  • Funding Mechanism:
    NIH: R01 (NIAID)
    Active Ingredient:
  • Citric Acid
  • L-lactic Acid
  • Potassium Bitartrate
  • QGriffithsin (QGRFT)
  • Product Indications:
  • Bacterial Vaginosis (BV)
  • Chlamydia
  • Gonorrhea
  • HIV
  • Pregnancy
  • Description:
    Multipurpose Vaginal pH Regulator (MVP-R™) with non-ARV (anti-retroviral) microbicide for the prevention of pregnancy and HIV.
    IMPT Secretariat
    1750 Howe Avenue, Suite 550
    Sacramento, CA 95825
    IMPT@cami-health.org

    The Initiative for Multipurpose Prevention Technologies (IMPT) is a project of CAMI Health, a social impact organization dedicated to improving the health of women and their families worldwide. CAMI Health is housed at the Public Health Institute (PHI).

    © Copyright 2020, Public Health Institute / CAMI Health / IMPT Secretariat. All rights reserved.