Multipurpose Prevention Technologies (MPTs) are an innovative class of products that deliver varied combinations of HIV prevention, other STI prevention, and contraception and will improve the lives of women and families worldwide.
This database includes MPT products that are currently funded and in active development. The database outlines detailed product information and can be searched to display products by desired criteria as selected from the drop-down boxes or by entering a keyword in the search box. Click on the product name to access detailed information on each product. Please note there are other MPT candidates not listed that may move forward pending funding. Click here to learn more about the inclusion criteria and information update methodology.
Click on the tables for MPT products in the development pipeline, listed by:
Know of an MPT product not included in this database or have updated information for listed products? Let us know here!
Amphora fast-dissolving vaginal insert (FDI)
MPT in Development
Development Stage:
Preclinical – Early (Pre1)
Hormonal/Non-Hormonal:
Non-Hormonal
Delivery Route & Method:
Topical -
Fast Dissolving Insert/Capsule-Vaginal
Mechanism of Action:
Amphora lowers vaginal pH (pH = 3.5-4.5) in the presence of semen. The low pH inactivates sperm and bacteria. Gel coats vaginal and cervical mucosa and prevents sperm penetration.
Developer:
Evofem Biosciences, Inc.
Population Council
Funding:
Nat. Institute Allergy & Infect. Diseases (NIAID)
National Institutes of Health (NIH)
Funding Mechanism:
NIH: R01 (NIAID)
Active Ingredient:
Citric Acid
L-lactic Acid
Potassium Bitartrate
Product Indications:
Bacterial Vaginosis (BV)
Chlamydia
Gonorrhea
Pregnancy
Description: An on-demand fast dissolve vaginal insert (FDI) MPT vaginal pH regulator (MVP-R™) for pregnancy prevention.
IMPT Secretariat
1750 Howe Avenue, Suite 550
Sacramento, CA 95825 IMPT@cami-health.org
