This database includes MPT products that are currently available, as well as MPT products in active development. The database outlines detailed product information and can be searched to display products by desired criteria as selected from the drop-down boxes or by entering a keyword in the search box. Click on the product name to access detailed information on each product. Click here to learn more about the inclusion criteria and information update methodology.
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Click on the table for MPT products in the development pipeline by indication combination.
MPT in Development
Mapp Biopharmaceutical, Inc.
Nat. Institute Allergy & Infect. Diseases (NIAID)
Clinical – Phase 0 Trial (C0)
Delivery Route & Method:
Topical - Film - Vaginal
Mechanism of Action:
virus neutralization, mucus trapping, and sperm agglutination
Description: Plant produced antibodies to HSV, and HIV were GMP manufactured and formulated for a Phase 1 clinical trial of HSV/HIV film that ended in 2019. The next generation of MB66 (MB66+) will include an anti-sperm human contraceptive antibody (HCA); a contraceptive surrogate efficacy trial will be conducted in 2020/2021.
This project is made possible by the generous support of the American people through the United States Agency for International Development (USAID) under the terms of Cooperative Agreement #AID-OAA-A-16-00045. The contents are the responsibility of the IMPT, CAMI Health, PHI, and its partners and do not necessarily reflect the views of USAID or the U.S. Government.