MPT Product Development Database

This database includes MPT products that are currently available, as well as MPT products in active development. The database outlines detailed product information and can be searched to display products by desired criteria as selected from the drop-down boxes or by entering a keyword in the search box. Click on the product name to access detailed information on each product. Please note there are other MPT candidates not listed that may move forward pending funding. Click here to learn more about the inclusion criteria and information update methodology.
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Click on the table for MPT products in the development pipeline by indication combination.
Hormonal/Non-HormonalDelivery RouteDelivery MethodDevelopment Stage
IndicationProduct DeveloperProduct Sponsor/FundingActive Ingredient
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25 product(s) found

Novel mAb contraceptive + TDF IVR

MPT in Development

Development Stage:
Preclinical – Early (Pre1)
Delivery Route & Method:
Topical - Intravaginal Ring (IVR)
Mechanism of Action:
Nucleoside analogue reverse transcriptase inhibitor (NRTI) and sperm agglutinating antibody
  • Oak Crest Institute of Science
  • University of North Carolina, Chapel Hill
  • Funding:
  • Nat. Institute Child Health & Human Development (NICHD)
  • Funding Mechanism:
    NICHD: R01
    Active Ingredient:
  • Monoclonal Antibodies
  • Tenofovir Disoproxil Fumarate (TDF)
  • Product Indications:
  • HIV
  • Pregnancy
  • Description:
    Formulation of a novel, nonhormonal contraceptive agent based on a multivalent monoclonal antibody (mAb) that blocks sperm from swimming through mucus and accessing the egg with antiretroviral (ARV) agents with demonstrated clinical efficacy in preventing HIV in a behavior-monitoring IVR.
    IMPT Secretariat
    1750 Howe Avenue, Suite 550
    Sacramento, CA 95825

    The Initiative for Multipurpose Prevention Technologies (IMPT) is a project of CAMI Health, an organization dedicated to advancing the comprehensive sexual and reproductive health of women and girls worldwide. CAMI Health is housed at the Public Health Institute (PHI).

    © Copyright 2020, Public Health Institute / CAMI Health / IMPT Secretariat. All rights reserved.